Facts About Blebbistatin Revealed
Schematic representation of activated and inhibited Wnt/β-catenin pathway. “WNT ON state�? Upon ligation of Wnts to their receptors made up of frizzled proteins and LRP5/six, the cytoplasmic protein DVL is activated and induces the suppression of GSK3β. Subsequently, stabilized β-catenin translocates to the nucleus and binds to TCF/LEF trans